The reason why has been a longstanding debate in the field.
The representatives of this group are: Benzodiazepines are the most widely used group of sedative drugs.Abuse may lead to severe psychological or physical dependence.Has a potential for abuse less than those in schedules 1 and 2.Antihistamines are used in the treatment of allergic reactions, colds, hay fever, hives, and insect bites and stings.Some antihistamines may also be helpful in reducing anxiety, inducing sleep, or at preventing or treating motion sickness.The representatives of this group are: Nonbenzodiazepine “Z-drugs” sedative-hypnotics are drugs that differ in structure from benzodiazepines, but acts on a subset of the benzodiazepine receptor family known as BZ1.
Their onset of action is rapid, and they are considered the preferred hypnotics as they do not significantly alter the various sleep stages due to their relative selectivity for the aforementioned receptor.
However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Sedation.
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
Barbiturates are nonselective CNS depressants that used to be the mainstay of treatment to sedate patients or to induce and maintain sleep.
In modern medicine they have been largely replaced by the benzodiazepines, primarily because they can induce tolerance, physical dependence and serious withdrawal symptoms.
The representatives of this group are: Certain antihistamines with sedating properties (also known as first-generation antihistamines) are effective in treating mild forms of insomnia, although numerous undesirable side effects (such as their anticholinergic properties) make them less useful in comparison with benzodiazepines.